The Effect by of Inspiring High Concentration Oxygen on the Reactive Oxygen Species in the Rats Brain Homogenates
- VernacularTitle:吸入高浓度氧对大鼠脑组织匀浆内活性氧的影响
- Author:
Yixuan MA
;
Xiaojun PAN
;
Hai ZHOU
;
Wenlong ZHU
- Publication Type:Journal Article
- Keywords:
High concentration oxygen;
Brain homogenates;
Reactive oxygen species
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the security of inspiring high concentration oxygen by detecting the reactive oxygen species of the rats brain homogenates after inspiring high concentration oxygen for a certain time.Methods Sixty wister rats weighting 150~200g were randomly devided into five groups(the group of 4h、8h、12h、16h and the control group,12/group).The experimental rats were exposed to 85%~100% oxygen in a self-made chamber and the control animals were kept in normal room air.The Concentration of the MDA,SOD,GSH,NO,NOS,CAT and T-AOC of the brain homogenates was detected.Results Compared with the control group,the level of MDA,NO and NOS in the brain homogenates grew up markedly(P
