Polycythaemia vera in JAK2 Era.
- VernacularTitle:基因突变与真性红细胞增多症
- Author:
Liansheng ZHANG
- Publication Type:Journal Article
- Keywords:
polycythaemia vera;
JAK2 gene;
gene mutation
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The discovery of an acquired mutation affecting the gene for janus kinase 2(JAK2 V617F)in a high proportion of patients with polycythaemia vera(PV)represents a major breakthrough in molecular understanding of the PV.This article will review the impact of the JAK2 mutation on the diagnosis and treatment of PV.