Application of hepatoprotectors in prevention and treatment of NAFLD.
- VernacularTitle:保肝药物防治非酒精性脂肪性肝病临床价值
- Author:
Yuyuan LI
- Publication Type:Journal Article
- Keywords:
hepatoprotectors;
NAFLD
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Hepatoprotectors including antioxidant supplements(Vit E,silymarin,GSH,betaine,ect.)and others(essentiale,UDCA,tiopronin,Glycyrrhiza preparation,pentoxifylline,ect.)have been considered reasonable approaches to nonalcoholic fatty liver disease(NAFLD).However the evidence-based medicine shows that they can improve symptoms and decrease aminotransferases levels.There is no sufficient evidence to support their effect on the improvement of histological changes and the natural history of NAFLD.These kinds of medicines with 1 to 2 drugs being selected in one prescription are recommended to the patients with nonalcoholic steatohepatitis(NASH).Basic regimens for the treatment should be concomitant to enhance their efficacy.
