Research progress in mesenchymal stem cell and blood-brain barrier permeability
10.3760/cma.j.issn.1673-4181.2010.03.015
- VernacularTitle:间质干细胞与血脑屏障通透性的研究进展
- Author:
Liping ZHOU
;
Qin YU
;
Yanping DUAN
- Publication Type:Journal Article
- Keywords:
Mesenchymal stem cells;
Blood-brain barrier;
Permeability;
Vitro model
- From:
International Journal of Biomedical Engineering
2010;33(3):-
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells(MSCs), which can be introduced in brain tissue by the strategies of brain parenchyma, blood and neurolymph transplantation, to repair tissue injury and promote functional recovery of neural system, have been considered as the ideal seed cells for the treatment of central nervous system diseases. However, as the special structure exists in the blood-brain barrier, study on correlation between MSCs and blood-brain barrier permeability will make it possible for more MSCs to pass the barrier to perform the treatment. This paper gives a review on the latest research development in the field.
