A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study.
- Author:
Da Hye SON
1
;
Su Hyun YOO
;
Ho Seok SA
;
Kyung Ja CHO
Author Information
1. Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. kjc@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Solitary fibrous tumors;
Giant cells;
Lacrimal apparatus;
Orbit
- MeSH:
Actins;
Angiofibroma;
Eyelids;
Giant Cells;
Hemangiopericytoma;
Histiocytoma, Benign Fibrous;
Lacrimal Apparatus;
Muscle, Smooth;
Orbit;
S100 Proteins;
Solitary Fibrous Tumors
- From:Korean Journal of Pathology
2013;47(2):158-162
- CountryRepublic of Korea
- Language:English
-
Abstract:
Orbital solitary fibrous tumor (SFT) has recently been proposed as the encompassing terminology for hemangiopericytoma, giant cell angiofibroma (GCAF), and fibrous histiocytoma of the orbit. The lacrimal gland is a very rare location for both SFT and GCAF. A 39-year-old man presented with a painless left upper eyelid mass. An orbital computed tomography scan identified a 1.1 cm-sized well-defined nodule located in the left lacrimal gland. He underwent a mass excision. Histopathologic examination showed a proliferation of relatively uniform spindle cells with a patternless or focally storiform pattern. Dilated vessels were prominent, but angiectoid spaces lined with giant cells were absent. Floret-type giant cells were mostly scattered in the periphery. The tumor was immunoreactive for CD34 and CD99, but negative for smooth muscle actin and S-100 protein. This is the first Korean case of SFT of the lacrimal gland with overlapping features of GCAF, suggesting a close relationship between the two entities.
