Chemoattractive effects of chemokine-like factor 1 on human arterial smooth muscle cells
- VernacularTitle:人趋化素样因子1对人动脉血管平滑肌细胞的趋化作用
- Author:
Chengrui XUAN
;
Yao CHEN
;
Peiying HE
;
Chenyang SHEN
- Publication Type:Journal Article
- Keywords:
Chemotactin factors;
Myocytes,smooth Muscle;
Chemotaxis;
Atherosclerosis
- From:
Journal of Peking University(Health Sciences)
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05) between the two groups diluted by 100-fold and 1 000-fold supernatants.When ASMCs were treated at different concentrations of 0 and 2 ?g/L of pertussis toxin(PTX),the cell number migrated from the test and control groups diluted by 10-fold supernatants,they had statistical significance(74?4 vs 34?3,P0.05).Conclusion:CKLF1 has significant chemotactic effects on ASMCs and such a CKLF1-induced chemotaxis could be inhibiteded by PTX at concentration of 10 ?g/L.
