Preparation of magnetic resonance molecular probe for breast cancer detection in vitro
- VernacularTitle:乳腺癌特异性磁共振分子探针的制备及体外实验
- Author:
Xubin LI
;
Xiangke DU
;
Tianlong HUO
;
Xia LIU
;
Sen ZHANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Magnetic resonance imaging;
Receptors,somatostatin;
Molecular probe
- From:
Journal of Peking University(Health Sciences)
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).There was remarkable low signal intensity on T2-weighed imaging and no evident artifacts for molecular probe when the concentration of Fe2+ was 20 mg/L.The least number of labeled cells detected by MR in vitro was 6?106 when the concentration of Fe2+ was 20 mg/L.Conclusion:Molecular probe,SPIO-OCT,can effectively label breast cells which express SSTR.The reasonable Fe2+ concentration of labeled cells and imaging was 20 mg/L.There is a correlation between MR signal intensity in vitro and the number of labeled cells.
