Alcohol-induced Liver Injury Model Study in Mice Using Silk Fibroin/Traditional Chinese Medicine Complex
- VernacularTitle:蚕丝蛋白/中药复合物对酒精性肝损伤模型小鼠的实验研究
- Author:
Yongqiang ZHU
;
Kemin WEI
;
Liangjun ZHU
- Publication Type:Journal Article
- Keywords:
Silk fibroin/traditional chinese medicine complex;
Alcohol-induced liver injury;
Protect
- From:
Journal of Medical Research
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effectiveness of Silk Fibroin Hydrolytes/Traditional Chinese Medicine Complex on prevention of alcohol-induced liver injury in mice.Methods Establish acute alcoholism liver injury models using alcohol(50 %).Experimental mice were randomly divided into five groups:control group,model group,small dose level group,middle dose level group and high dose level group.Control group and model group were given distilled water BW/d 20ml/kg,and the three sample groups were given different level of Silk Fibroin Hydrolytes/Traditional Chinese Medicine Complex for 30 days continuously.Results Content of MDA,GSH and TG in mice livers have significant difference in the middle and high dose level groups compared with model group(P
