Influence of Different Interventions on Insulin Resistance and ?-cell Function in Patients with Impaired Glucose Tolerance
- VernacularTitle:不同干预方法对糖耐量减低胰岛素抵抗和胰岛?细胞功能的影响
- Author:
Hongguang DING
;
Pengying LIU
;
Junying LIU
;
Ji PENG
;
Jingfan XIONG
;
Jie XIAO
;
Ying LI
;
Lei WU
;
Yaohui HUANG
- Publication Type:Journal Article
- Keywords:
Impaired glucose tolerance;
Insulin resistance;
?-cell function;
Intervention
- From:
Journal of Medical Research
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of different interventios on insulin resistance and ?-cell function in population with impaired glucose tolerance(impaired glucose tolerance,IGT).Methods The total of 382 cases of IGT were divided into five groups according to interventions:control(C),diet plus exercise group(D+E),Acarbose Group(A),Metformin(M)and traditional Chinese medicine Group(TCM),with each group making the appropriate intervention programmes.BMI,FPG,2hPG,F-Ins,P-Ins,F-CP and P-CP were determined before intervention and yearly during the follow up,and BMI,HOMA-IR,HOMA-? were calculated.Results By the end of the study,insulin,F-CP,IR Group D+E and FPG,2hPG,insulin,C-peptide,IR in the other groups were significantly lower than before the intervention(P
