Clinical Manifestations of Rheumatoid Arthritis and Concurrent Systemic Lupus Erythematosus
- VernacularTitle:类风湿关节炎合并系统性红斑狼疮临床分析
- Author:
Xi QIAO
;
Rongshan LI
;
Liyun ZHANG
- Publication Type:Journal Article
- Keywords:
Arthritis;
Rheumatoid;
Lupus erythematosus;
Systemic;
Rhupus syndrome
- From:
Journal of Medical Research
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical manifestations of coexistent rheumatoid arthritis(RA)and systemic lupus erythematosus(SLE)(Rhupus syndrome).Methods Clinical data from a patient with Rhupus syndrome were analyzed combined with literature review.Results The patient was a middle-aged female,who presented with features of RA and developed features of SLE 7 years later.Renal involvement in common cases is rare but presented in our patient with severe renal dysfunction.The patient showed part remission with glucocorticosteroids and cyclophosphamide therapy.Conclusion Rhupus syndrome is a rare condition sharing features of RA and SLE.These patients present with features of one disease but later on develop features of another.Glucocorticosteroids and immune suppressors are effective.Appreciation of these patients with rhupus is important since their therapy and outcome differ from those having RA or SLE alone.