Changes of Serum Vascular Endothelial Growth Factor before and after Interventional Therapy and Their Clinical Significance in Patients with Hepatocellular Carcinoma
- VernacularTitle:sVEGF在原发性肝癌介入治疗前后动态变化及其意义
- Author:
Huasheng GAO
;
Guangping LU
- Publication Type:Journal Article
- Keywords:
Carcinoma;
Hepatocellular;
Embolization;
Vascular endothelial growth factors;
Metastasis;
Recurrence;
Angiogenesis;
Anti-angiogenesis;
Therapeutic
- From:
Journal of Medical Research
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of serum vascular endothelial growth factor(VEGF)levels before and after interventional therapy of hepatocellular carcinoma(HCC),in order to find out a experimental proof that can start the anti-angiogenesis therapy.Methods Enzyme linked immunosorbentassay(ELISA)was used to detect serum levels of VEGF before transcathter arterial chemo-ebolization and in 24 hours,72 hours,7 days,14 days,30 days,after the operation,in 50 healthy individuals and 54 HCC pationts.Results Serum levels of VEGF in 54 patients with HCC were significantly higher than those in healthy individuals(P
