The advantage and disadvantage of intensive glucose control on the latest evidence-based medicine.
- VernacularTitle:从最新循证医学证据看强化降糖治疗的利弊
- Author:
Dandan ZHANG
;
Yiming MU
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
evidence-based medicine;
intensive glucose control
- From:
Chinese Journal of Practical Internal Medicine
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
ADVANCE trial demonstrated that stable intensive glucose control could improve prognosis and the target HbA1c should be 6.5%.While ACCORD and VADT trials suggested aggressive glucose lowering in diabetics at high cardiovascular risk is potentially harmful,tight glucose control yields no significant effect on long duration,poorly controlled patients with complications.DCCT and UKPDS research confirmed benefits of early intensive glucose control could persist due to legacy effect.Steno-2 research showed patients benefit greatly from comprehensive control of risk factors.In sum,early intensive control of risk factors and individualized treatment in diabetics are mainstream therapy.
