Predictive Factor to Regain Erectile Function after Bilateral Nerve Sparing Radical Retropubic Prostatectomy in Korean Men.
10.4111/kju.2007.48.3.283
- Author:
In Ho CHANG
1
;
Jun Hyun HAN
;
Ji Hyeong YU
;
Byung Kyu HAN
;
Seong Jin JEONG
;
Sung Kyu HONG
;
Seok Soo BYUN
;
Sang Eun LEE
Author Information
1. Department of Urology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. selee@snubh.org
- Publication Type:Original Article
- Keywords:
Prostate cancer;
Prostatectomy;
Erectile dysfunction
- MeSH:
Coitus;
Erectile Dysfunction;
Follow-Up Studies;
Humans;
Male;
Multivariate Analysis;
Odds Ratio;
Phosphodiesterase 5 Inhibitors;
Preoperative Period;
Prostatectomy*;
Prostatic Neoplasms;
Questionnaires;
Retrospective Studies
- From:Korean Journal of Urology
2007;48(3):283-290
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the significance of various preoperative factors with regard to postoperative erectile function in Korean men undergoing a bilateral nerve sparing radical retropubic prostatectomy (BNSRRP), using the validated Korean version of the International Index of Erectile Function (IIEF-5). MATERIALS AND METHODS: Between March 2004 and March 2005, 83 consecutive patients, who underwent a BNSRRP, with preoperative IIEF-5 scores greater than 13, were retrospectively analyzed. All patients were asked to answer the IIEF-5 questionnaire during the preoperative period and 1 year postoperatively. The responses were stratified on the basis of the clinical characteristics and the preoperative predictive factors for regaining a normal erectile function (NEF: IIEF-5 score> or =18) investigated. RESULTS: At the baseline, 56 patients (67.5%) had NEF. At the 1 year follow-up after the BNSRRP, 58 (70.5%) patients reported a return of a sufficient erection for sexual intercourse, with or without oral phosphodiesterase type 5 (PDE5) inhibitors, but 37 (44.6%) patients regained a NEF. Of these 37 patients, 15 (40.5%) were able to spontaneously regain a NEF, but 22 (59.5%) needed the help of oral PDE5 inhibitors. When the patients were divided according to postoperative NEF and erectile dysfunction (ED: 14< or =IIEF-5 score<18), the preoperative IIEF-5 score was the only significant factor for predicting postoperative NEF after a BNSRRP in univariate (p=0.018) and multivariate analyses [p=0.030, odds ratio: 3.482, 95% confidence interval (CI): 1.125-10.774]. Changes in the IIEF-5 score after a BNSRRP significantly decreased for those with preoperative NEF compared with ED ( 6.1+/-5.24 vs. 9.1+/-7.34, p=0.039). CONCLUSIONS: Our data indicated that preoperative erectile function, as assessed using the IIEF-5 questionnaire, was an independent variable for predicting the recovery of erectile function after a BNSRRP when performed in Korean men.
