Distributions of Alleles and Haplotypes of HLA - DRB1, - DQA1 and - DQB1 in Koreans.
- Author:
Hoon HAN
;
Tai Gyu KIM
;
Hee Baeg CHOI
;
Te June CHUNG
;
Seo Young CHUNG
;
Chang Kyu KIM
- Publication Type:Original Article
- Keywords:
HLA-DRB1;
DQA1;
DQB1;
Haplotype
- MeSH:
Alleles*;
Genotype;
Haplotypes*;
HLA-DRB1 Chains
- From:Korean Journal of Immunology
1998;20(1):47-54
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The thirteen DRB1, 6 DQA1, and 5 DQB1 alleles were defined in 362 healthy Korean controls using reverse dot blot hybridization method. The twenty-four immobilized SSOs for DRB1, 8 for DQA1, and 6 for DQB1 were used for this study. The frequencies of genotypes were DRB104 (17.1'Yo), '09 (13.1%), and '13 (11.6%); DQA1'01 (46.7%), 03 (30.8%), and '05 (11.7%); DQB1*03 (39.5%), '06 '(29.8%), and 05 (16.0%). ...continue...