Relationship of heparanase and bFGF expressions with angiogenesis in human ovarian carcinoma: report of 41 cases
- VernacularTitle:肝素酶、bFGF在卵巢癌中的表达及与其血管生成的关系
- Author:
Jing HAN
;
Hao ZHANG
;
Ying YANG
;
Yan LIAN
- Publication Type:Journal Article
- Keywords:
ovarian cancer;
immunohistochemistry;
heparanase;
basic fibroblast growth factor
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expressions of heparanase(Hpa) and basic fibroblast growth factor(bFGF) as well as their relationship with angiogenesis in human ovarian carcinoma.MethodsForty-one ovarian carcinoma specimens resected from the patients diagnosed with ovarian carcinoma from January 2003 to November 2007 were examined by immunohistochemistry for the expressions of Hpa and bFGF and microvessel density(MVD).ResultsHpa highly expressed in ovarian carcinoma,and its expression was positively correlated with MVD and bFGF expression(r=0.351,P
