Changes of CD4~+,CD25~+,Foxp3~+ Regulatory T Cells in Patients with Esophageal Carcinoma and Its Possible Clinical Significance
- VernacularTitle:食道癌患者CD4~+、CD25~+、Foxp3~+调节性T细胞的变化及意义
- Author:
Zhengjun HU
;
Shengjun WANG
;
Yuan LI
- Publication Type:Journal Article
- Keywords:
esophageal carcinoma;
CD4+,CD25+regulatory T cells;
forkhead/ winged helix transcription factor
- From:
Journal of Zhejiang Chinese Medical University
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the changes of CD4+CD25+Foxp3+regulatory T cells (Tregs) in peripheral blood of patients with esophageal carcinoma and its possible clinical significance.[Methods] The flow cytometry was used to evaluate the population of CD4+,CD25+,Foxp3+T cells in the peripheral blood of the patients with esophageal carcinoma before therapy and of the healthy donors.[Results] The percentage of CD4+,CD25+,Foxp3+T cells of the esophageal carcinoma group before therapy was significantly higher than the healthy donors group (P
