The cerebral protective effect of a medicinal formula in mice with ischemia/reperfusion induced brain injuries
- Author:
Tran Luu Van Hien
- Publication Type:Journal Article
- Keywords:
“activating the blood and clearing the obstruction” formula, Ischemia
- MeSH:
Brain Injuries;
Mice;
Ischemia;
Reperfusion
- From:Journal of Medicinal Materials - Hanoi
2005;10(3):96-98
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The experimental trials was conducted on Swiss white mice of 7 weeks of age, both sexes, and weight of 20-22g. Results: SOD activity in mice with ischemia/reperfusion was significantly statistical lower than those in the control group, p<0.05. In the group treated by “activating the blood and clearing the obstruction” formula with dose of 200 mg/kg, SOD activity was lower than those in the research group (89.5%) and was 73.7% compared to control group. In the group treated by this formula with dose of 300 mg/kg, SOD content was still lower than those in the research group (96%) and was 79.5% compared to control group. In the group treated by the dose of 500 mg/kg, SOD activity was higher significantly than those in the research group (113.6%) and was 96% compared to control group. The result showed that with appropriate dose, this medicinal formula has antioxidant effects
