Effect of active compound components of SQ on MMP-1,TIMP-1,VEGF,t-PA and PAI-1 of in? ammatory endometrial cell
- VernacularTitle:三七复合有效成分对人子宫内膜炎症细胞MMP-1、TIMP-1、VEGF及t-PA、PAI-1的影响
- Author:
Qing DING
;
Zhaoling YOU
;
Zhenyu TAN
- Publication Type:Journal Article
- Keywords:
The active compound components of SQ;
Endometrial cell;
Inflammation;
MMP-1;
TIMP-1;
VEGF;
t-PA;
PAI-1
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To study the effect of MMP-1,TIMP-1,VEGF and t-PA,PAI-1 in the inflammatory process of endometrium cell and the active components of SQ.Methods: ICC,ISH and WB was used to test the level of protein of MMP-1,TIMP-1,VEGF and t-PA,PAI-1 and mRNA of MMP-1,TIMP-1 and VEGF of endometrium cell in regular group,pattern group,GongXueNing group and SQ group.Result: In contrast with model group,the level of MMP-1protein and mRNA expression obviously decreased,but the level of TIMP-1 and VEGF increased in SQ group,there were signifi cant differences(P
