The Clinical Usefulness of Combination Assay of MG7 - Ag and CEA in Gastric Cancer.
- Author:
Kyung Ok LEE
;
Kyung In KIM
;
Kyu Pum LEE
- Publication Type:Original Article
- Keywords:
MG7-Ag;
CEA;
Gastric cancer
- MeSH:
Humans;
Mass Screening;
Stomach Neoplasms*
- From:Korean Journal of Immunology
1998;20(1):81-84
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recently new tumor marker, MG7-Ag has been introduced for screening of gastric cancer. In this study MG7-Ag and CEA in sera of 50 normal healthy Koreans and 48 patients with gastric cancer group were determined to elucidate the clinical usefulness for gastric cancer screening. Commercial Enzyme Immuno Assay kits were used for analysis of above two markers. Sensitivity of MG7-Ag and CEA in patient group were found to be 43.8% and 41.7%, respectively. When the two markers were used combind, sensitivity increased to 62.5%. The concentration of MG7-Ag in patients (9.2+11.7 U/mL) was five times higher than normal control group (1.81+1.63 U/mL). CEA was 31.2+46.5 ng/mL in patients and 2.24+0.98 ng/mL (MeanSD) in normal control group. From this results, combination assay of MG7-Ag and CEA is more useful in clinical laboratories for screening gastric cancer than using one marker.
