The relationship between the imbalance of the Th1/Th2 cytokines and autoimmune thyroid disease.
- VernacularTitle:Th1/Th2细胞平衡偏移与自身免疫性甲状腺疾病的相关性研究
- Author:
Hao SHEN
;
Ling HU
- Publication Type:Journal Article
- Keywords:
cytokine;
Th1/Th2;
AITD
- From:
Chinese Journal of Practical Internal Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analysis the serum levels of the Th1/Th2 cytokines interleukine-2 and interleukine-5 in patients with autoimmune thyroid disease(AITD) and investigate the relationship between the imbalance of Th1/Th2 cytokines and the pathogenesis of AITD.Methods 20 healthy as controls and 75 patients were studied.45 patients suffered from GD,30 patients suffered from HT.The serum concentrations of interleukine-2(IL-2) and interleukin-5(IL-5),representative cytokines of Th1 and Th2 cells respectively,were assayed by enzyme-linked immunosorbent assay(ELISA).Results(1)Compared with HT group and controls,the concentration of IL-5 in GD group was remarkably increased(P
