Effects of Tsaoko-anemarrhenae Decoction on Apoptosis of the Hippocampal Neurons and it′s Gene Expression in Epileptic Rat Models.
- VernacularTitle:草果知母汤对癫痫大鼠海马神经元凋亡及基因表达的影响
- Author:
Liping ZHANG
;
Meng XIA
- Publication Type:Journal Article
- Keywords:
Epilepsy;
Apoptosis;
Gene expression;
Tsaoko-anemarrhenae decoction
- From:
Journal of Medical Research
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Epilepsy was arousing the attention of medical circles because of the complexity of its mechanism and the difficulty of its control.The project which used the pioneering research as the basement and was directed by the chinese medicine used the modern multidisciplinary research technologies and explored the mechanism of the brain damage in epilesy.The project′s treatment idea is different from the others,which provided a new way for seeking new medicines for treating epilepsy.The research techniques took use of the application of the behavioral methods and the electrophysiological methods creatively and the subject firstly used this way to observe it dynamically,which greatly improved the accuracy of evaluating the models and pharmacodynamics studies of the epilepsy.The research method of the project firstly observed the changing mechanism of the brain damage and the regulation of the apoptosis related genes,and even the efficiency of tsaoko-anemarrhenae decoction,which enriched the scientific intension of the decoction.The conclusions palyed a very important role in exploiting the new medicine for treating epilepsy and enriching the knowledge of the five visceras in chinese medicine.
