Effect of modified Dihuang decoction on expression of c-fos positive neuronin in hippocampal CA1 area in diabetic rats
- VernacularTitle:加减地黄饮子对糖尿病大鼠海马CA1区神经元c-fos表达的影响
- Author:
Yanju WEI
;
Yueming ZHANG
- Publication Type:Journal Article
- Keywords:
Modified Dihuang decoction;
Diabetes;
Hippocampus;
c-fos
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of modified Dihuang decoction on expression of c-fos positive neuron in hippocampal CA1 area in diabetic rats. Methods:The diabetic rat models were induced by intraperitoneal injection of streptozotocin(STZ) . 4 weeks later,the expression of c-fos was detected by immuno-histochemistry. Results:Compared with diabetes group(9.25?2.36,0.56 ?0.06) ,the positive cell's density and average light density(8.13?1.70,0.46?0.08) of c-fos positive neuron in hippocampal CA1 area in diabetic rats which were prevented and treated with modified Dihuang decoction both decreased(P
