Influence of Qingzhifugan Pellet on fatty liver animal model with chronic hyperlipemia and alcoholized hepatic damage
- VernacularTitle:清脂复肝颗粒对慢性高脂血症与乙醇肝损伤混合型脂肪肝动物模型的影响
- Author:
Bo YANG
;
Shuyan WANG
;
Fangzhou LIU
;
Xiuyun MA
;
Guolong ZHAO
- Publication Type:Journal Article
- Keywords:
Chronic fatty liver(mixed-type);
Animal model;
Qingzhifugan pellet;
Therapeutic experiment
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe influence of qingzhifugan pellet on mixed-type animal model of fatty liver with chronic hyperlipemia and alcoholized hepatic damage. Methods:The mixed-type animal model of fatty liver was established by administering with high lipids and alcohol feeds. Therapeutic experiments were conducted with a self-made new drug the qingzhifugan pellet. The efficacy of the tested drug was evaluated comprehensively by such measures as sero-level of lipids and ferments,as well as the histological pathology of liver. Results:It was shown that the tested drug can decrease the sero-level of lipids,promote the metabolism of lipids in liver,recover the alcoholized hepatic damage,and relieve the liver fat denaturation. Conclusion:It suggested that the tested drug possessed certain effect for treating or improving chronic hyperlipemia and alcoholized hepatic damage in the animal model.
