Antiplatelet therapy for ischemic cerebrovascular diseases
- VernacularTitle:抗血小板药物治疗缺血性脑血管病的合理应用
- Author:
Fang QU
;
Xin CHEN
- Publication Type:Journal Article
- Keywords:
antiplatelet drugs;
ischemic cerebrovascular diseases;
aspirin;
clopidogrel;
dipyridamole
- From:
Chinese Journal of Practical Internal Medicine
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Antiplatelet therapy is a major strategy with a growing body of evidence in management of ischemic cerebrovascular diseases.This article introduces the mechanism of currently available antiplatelet drugs as well as their practice guidelines and evidence from clinical trials.There is currently no robust evidence to support the use of venous antiplatelet agents.Aspirin is the sole evidence-based antiplatelet drug for treatment of acute ischemic stroke.Aspirin,dipyridamole and clopidogrel are effective in secondary stroke prevention.Combination therapy using aspirin plus extended-release dipyridamole is the only combination approach to demonstrate additive benefit.
