Current progress on drug therapy for amyotrophic lateral sclerosis
- VernacularTitle:肌萎缩侧索硬化药物治疗进展
- Author:
Hongsong SONG
;
Dongsheng FAN
- Publication Type:Journal Article
- Keywords:
amyotrophic lateral sclerosis;
anti-excited aminoacid;
neurotrophic factor;
mitochondrial function
- From:
Chinese Journal of Practical Internal Medicine
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Amyotrophic lateral sclerosis is a rare but fatal neurodegenerative disorder.Riluzole remains the only available drug for slowing the progression of the disease.In the past few years,significant advances have been made in both our understanding of pathogenesis and the development of new therapeutic approaches.The authors review the current understanding of the pathogeneic mechanisms and drug therapy.The outcome of phase Ⅲ clinical trials will benefit the further investigation in ALS.