Multivoxel ~1H-MRS for contusion and laceration area of mild-to-moderate traumatic brain injury with in adults
- VernacularTitle:成人轻中型颅脑损伤挫裂伤区域的多体素~1H-MRS研究
- Author:
Yang ZHANG
;
Haitao LI
;
Bing XIE
;
Chuan LI
- Publication Type:Journal Article
- Keywords:
proton magnetic resonance spectroscopy;
traumatic brain injury;
Glasgow coma score
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of multivoxel proton magnetic resonance spectroscopy(1H-MRS) in contusion and laceration area of mild-to-moderate traumatic brain injury(TBI) in adults.Methods Twenty-eight TBI patients definitely diagnosed were recruited in this study,including 16 moderate TBI whose Glasgow coma scores were in 9-12 and 12 mild TBI whose Glasgow coma scores were in 13-15.The spectrum for NAA,Cho,Cr and other metabolite peaks in contusion and laceration area were measured and NAA/Cr,NAA/Cho,Cho/Cr ratios were calculated for each voxel.Results In multivoxel 1H-MRS for the lesion areas,the ratios of NAA/Cr,NAA/Cho and Cho/Cr changed significantly compared with those of 16 normal controls(P0.05).Conclusion Multivoxel 1H-MRS may have an important clinical value in detecting and assessing early mild-to-moderate brain trauma.NAA/Cr ratio of the injured region can reflect the severity of cerebral injury.
