Effect of TNF-? on F-actin of `from guinea pig cochlea
- VernacularTitle:肿瘤坏死因子对豚鼠耳蜗血管纹微血管内皮细胞纤维肌动蛋白的影响
- Author:
Qi LI
;
Xueyuan ZHANG
- Publication Type:Journal Article
- Keywords:
TNF-?;
F-actin;
strial capillary endothelial cells
- From:Journal of Third Military Medical University
1984;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of F-actin of strial capillary endothelial cells from guinea pig cochlea after TNF-? treatment so as to further study the mechanism of permeability of those cells.Methods Strial capillary endothelial cells were dissociated from guinea pig cochlea and cultured respectively with 0.05,0.1,0.2 ng/ml TNF-? for 90 min,then detected by immunofluorescence laser confocal microscopy for F-actin concentrations.The blank control was set simultaneously.Results TNF-? decreased the content of F-actin in strial capillary endothelial cells(P
