Effect of DuSuQing granula on expression of inflammatory factor in small intestine tissue of rabbit model of endotoxin-induced lung injury
- VernacularTitle:毒素清颗粒对内毒素肺损伤兔小肠炎性因子表达的影响
- Author:
Suyun LI
;
Jiansheng LI
;
Xiangyu WANG
;
Baojun LIU
- Publication Type:Journal Article
- Keywords:
Lung injury;
DuSuQing granula;
ICAM-1;
VCAM-1;
Endotoxin
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore effect of DuSuQing granula on expression of inflammatory factor in small intestine of rabbit model of endotoxin-induced lung injury .Method:Rabbit model of lung injury was established by intravenous injection of lipopolysaccharide.36 white male flap-eareds were randomly divided into six groups:Normal control group,model group,DSQ high dosage group,DSQ middle dosage group,DSQ low dosage group and ShuangHuangLian( SHL) group.The expression of macrophage,s TNF-?,ICAM-1,VCAM-1 in small intestine tissue were analyzed by immunohistochemistry.Results:The expression of macrophage,TNF-?,IL-1,ICAM-1,VCAM-1 in model group was markedly higher than that in normal group(P
