Effect of Bitongling Granule medicated serum on rabbit articular chondrocytes cultured in vitro
- VernacularTitle:痹痛灵颗粒含药血清对家兔关节软骨细胞体外培养的影响
- Author:
Min ZHANG
;
Yong WANG
;
Yuanyuan LI
;
Yingqian ZHAO
- Publication Type:Journal Article
- Keywords:
Osteoarthritis;
TCM therapy;
Chondrocyte;
Bitongling Granule;
NO;
SOD
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of Bitongling Granule medicated serum on rabbit articular chondrocytes cultured in vitro.Methods:Bitongling Granule(2ml/kg) was given to New Zealand rabbits for 3 days for preparation of containing serum.Rabbit.chondrocytes were divied into Bitongling Granule groups of different concentrations,blank serum group,experimental control group and anti-bone capsule group.To observe the change of nitric oxide synthase and superoxide dismutase in all groups.Results:Bitongling Granule can reduce the activity of NO and increase the level of SOD in sera.Conclusions:Bitongling Granule can prevent and cure experimental osteoarthritis,which is related to the decrease of NO and activation of SOD.
