The Use of Extracorporeal Circulation in Suspected Brain Dead Organ Donors with Cardiopulmonary Collapse.
10.3346/jkms.2015.30.12.1911
- Author:
Hyun LEE
1
;
Yang Hyun CHO
;
Kiick SUNG
;
Jeong Hoon YANG
;
Chi Ryang CHUNG
;
Kyeongman JEON
;
Gee Young SUH
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Extracorporeal Membrane Oxygenation;
Brain Death;
Tissue Organ Procurement
- MeSH:
Adult;
*Brain Death/diagnosis;
*Extracorporeal Membrane Oxygenation;
Female;
Heart Arrest;
Humans;
Male;
Middle Aged;
Organ Transplantation;
*Tissue Donors;
Tissue and Organ Harvesting;
Tissue and Organ Procurement/*methods;
Treatment Outcome;
Young Adult
- From:Journal of Korean Medical Science
2015;30(12):1911-1914
- CountryRepublic of Korea
- Language:English
-
Abstract:
Donor shortage is a major limitation in organ transplantation. Several studies have reported that extracorporeal membrane oxygenation (ECMO)-assisted organ donation can be successfully completed without inducing warm ischemia in patients with brain death. The present report described clinical experience of three patients (23-yr old man, 32-yr old man, and 41-yr old woman) who underwent ECMO for the evaluation of brain death and organ donation. They donated six kidneys, three livers, and one both lungs without warm ischemia by ECMO. Six kidney recipients successfully recovered normal status without hemodialysis and two liver recipients survived with normal liver functions, but one liver recipient and one lung recipient died 3 and 15 days after transplantation. Our report strongly encourages ECMO-assisted organ donation from brain death patients with refractory cardiopulmonary collapse to achieve improved organ transplantation.
