Clinical observation on effect of losartan associated with astragalus injection on early diabetic nephropathy
- VernacularTitle:氯沙坦联合黄芪注射液治疗早期糖尿病肾病80例临床观察
- Author:
Xiaolin XU
- Publication Type:Journal Article
- Keywords:
diabedic nephropathy;
losartan;
astragalus injection
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study investigated the effects and mechanisms of the combined use of Losartan and Astragalus injection for treatment of early diabetic nephropathy(DN) .Methods 80 cases of early DN patients were randomLy divided into 2groups.In the control group(n=40) the patients were received losartan(taken in morning) 50mg/d,while in the experiment group(n=40) received losartan(taken in morning) 50mg/d,associated with astragalus 60mL added in 0.9%solution of sodium chloride 100mL together driped by vein,q.d.Treatment courses lasted 4 weeks in both groups,U-Alb,MAP,FBG,TG,TC,,Scr and BUN were detected for all patient before and after therapy,the data obtained from two groups were compared each other and analysed statistically.Results Detected outcomes indicated that,after therapy,all patients,MAP、TC、TG、Whole blood viscosity、Viscosity of plasma、Fibrinogen and packed cell volume were all significantly reduced in the experiment group,It was more obvious than in the control group.Conclusion Combination of Losartan and Astragalus injection with conventional western medication has a better effect on the treatment of early DN than only Losartan with conventional western medication.
