Clinical Significance of Serum IL-18 and IL-18BP in Patients with Primary Liver Cancer
- VernacularTitle:原发性肝癌患者血清IL-18及IL-18BP水平的测定及临床意义
- Author:
Xianghui LIAO
;
Chengnong GUAN
;
Liangzhen CAI
- Publication Type:Journal Article
- Keywords:
Primary hepatic carcinoma(PHC);
Liver cirrhosis(LC);
Serum interleukin 18(sIL-18);
Serum interleukin 18 link albumen(sIL-18BP)
- From:
Journal of Medical Research
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationships between serum IL-18 and IL-18BP and the development,metastasis,curative effect and prognosis of primary liver cancer.Methods There were total 49 cases patients,of which 28 cases primary hepaticcarcinoma(PHC)and 21 cases liver cirrhosis(LC),and 18 cases heathy people.Their serum levels of IL-18 and IL-18BP were determined by using an ELISA assay and comparation.Results The serum IL-18 in PHC was significantly lower than that in LC and controls;the serum IL-18BP in PHC was significantly higher than that in LC and controls;the IL-18 and IL-18BP in LC were significantly higher than those in controls(P