Significance of Sera Cystatin C in Patients with Colorectal Cancer
- VernacularTitle:结直肠癌患者血清半胱氨酸蛋白酶抑制剂C的变化及临床意义
- Author:
Weigang HUANG
;
Rongce CHEN
;
Fujia CHEN
- Publication Type:Journal Article
- Keywords:
Cysteine proteinase inhibitor C;
Colorectal cancer
- From:
Journal of Medical Research
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance by detecting the levels of sera cystatin C(Cys C)in patients with colorectal cancer.Methods We compared the levels of sera cys C detected with the immune rate nephelometry(IRN)in 71 colorectal cancer patients.Then we compared it in 40 healthy persons and 48 colorectal disease patients without cancer to investigate the relationship between the level of cys C and the clinicopathological characteristics.Results The levels of cys C in colorectal cancer patients were much higher than those in the other control groups,and were significantly related to Dukes stages and the tumor differentiated degree.Conclusion The results provide convincing evidence that cys C may contribute to occurrence and development of colorectal cancer.