The Research Progress of P38 Signaling Pathway in Liver Ischemia Reperfusion Injury
- VernacularTitle:P38信号通路在肝脏缺血再灌注损伤中作用的研究进展
- Author:
Haiyan ZHANG
;
Hanfei HUANG
;
Zhong ZENG
- Publication Type:Journal Article
- Keywords:
p38;
liver;
ischemia reperfusion injury
- From:
Journal of Kunming Medical University
2014;(2):145-147,151
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic ischemia-reperfusion injury,a relatively common phenomenon in clinical pathophysiology, is one of the currently difficult and hot issues in liver surgery and liver transplantation clinical studies. p38 mitogen activated protein kinases are activated in a variety of diseases and stress conditions. p38 signaling pathway activation is one of the important mechanisms leading to hepatic ischemia-reperfusion injury. This article reviews the roles and mechanisms of P38 signaling pathway recently years in the liver ischemia reperfusion injury.