Effects of Xinfeng Capsule on platelet parameters,p-select,platelet ultrastructure and its therapeutic effect on rheumatoid arthritis patients in active phase
- VernacularTitle:类风湿关节炎活动期患者血小板参数、P-选择素和血小板超微结构的变化及新风胶囊对其的影响
- Author:
Jian LIU
;
Ruikai ZONG
;
Xuefang YU
;
Yuan WANG
- Publication Type:Journal Article
- Keywords:
Rheumatoid arthritis;
P-select;
PLT;
Platelet ultrastructure;
Xinfeng Capsule;
Clinical research
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe effects of Xinfeng Capsule(XFC)on platelet parameters(platelet count,thrombocytocrit,mean platelet volume,platelet distribution width),p-select,platelet ultrastructure and its therapeutic effect on rheumatoid arthritis(RA)patients in active phase.Methods:To detect platelet parameters,p-select and reactive indexes(ESR,?1-AGP,CRP,RF)of 60 RA patients in active phase.Patients were divided into XFC treated group(35 examples),Zhengqingfengtongning(ZQF)control group(25 examples)according to random digits table.After a course of treatment,to observe therapeutic effect and the changes of platelet parameters,p-select,reactive indexes of two groups.Setting up a normal control(20 examples)and detecting above-mentioned indexes.To observe platelet ultrastructure with transmission electron microscope.Results:1.Compared with normal control group,PLT,PCT,MPV,Ps of RA patients in active phase increased obviously(P0.05).But the excellence rate of XFC exceeded that of control group(P
