The relationship between leptin level BMI and helicobacter pylori infection in gastric ulcer
- VernacularTitle:胃溃疡患者血清瘦素 体重指数变化与幽门螺杆菌感染的关系研究
- Author:
Lei HE
;
Guangli GU
;
Xi LI
;
Hesheng LUO
- Publication Type:Journal Article
- Keywords:
helicobacter pylori;
leptin;
gastric ulcer;
body mass index
- From:
Chinese Journal of Practical Internal Medicine
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the leptin level and its relation with Hp infection in the gastric ulcer(GU).Methods Thirty-one Hp positive GU patients were chosen and divided into two groups,one group included 22 patients with successful eradication therapy on Hp and the other group included 9 patients with unsuccessful eradication therapy;12 Hp negative GU patients underwent anti-ulcer therapy;14 Hp negative normal persons were chosen as control.The BMI,serum leptin level,IL-8 mRNA and protein of gastric issue and symptom score were determined before and three month after the therapy.Results The expression of IL-8 protein and mRNA was obviously higher in Hp positive GU patients before therapy(P
