A case of low-grade endometrial stromal sarcoma with multiple metastasis.
- Author:
Han Byoul CHO
1
;
Jae Hoon KIM
;
Soon Won HONG
;
Hyun Joon LEE
;
Min Kyoung KIM
;
Sung Hoon KIM
;
Young Tae KIM
;
Jae Wook KIM
Author Information
1. Department of Obstetrics and Gynecology, Yong Dong Severance Hospital, Korea. jaehoonkim@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Low-grade endometrial stromal sarcoma (ESS);
Multiple metastasis
- MeSH:
Adult;
Drug Therapy, Combination;
Female;
Humans;
Leiomyosarcoma;
Mesoderm;
Neoplasm Metastasis*;
Sarcoma;
Sarcoma, Endometrial Stromal*
- From:Korean Journal of Obstetrics and Gynecology
2006;49(9):1993-1998
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Uterine sarcomas are rare tumors of mesodermal origin and constitute 2-6% of uterine malignancies. They are classified into leiomyosarcoma (LMS), malignant mixed mullerian tumors (MMMTs), and endometrial stromal sarcoma (ESS) by histologic types. Endometrial stromal sarcomas account for about 7-15% of uterine sarcomas, about 0.2% of female genital tract malignancies. Endometrial stromal sarcomas are divided into endometrial stromal nodule, low-grade endometrial stromal sarcoma, and high-grade endometrial stromal sarcoma on the basis of mitotic activity and vascular invasion. Clinical outcome of low-grade endometrial sarcoma is better than that of high-grade endometrial stromal sarcoma and has a propensity for slow metastasis. We have experienced a case of low-grade endometrial stromal sarcoma with multiple metastasis in a 41-year-old woman and was treated by surgical resection and combination chemotherapy, which is presented with a review of brief literature.