The comparison of 4 schemes for anesthesia in pediatric patients undergoing surgery of transcatheter ventricular septal defect closure
10.3969/j.issn.1671-8348.2013.25.013
- VernacularTitle:4种用药方案在小儿室间隔缺损介入封堵术麻醉中的比较
- Author:
Gang LI
;
Changhe REN
;
Gangming WU
;
Junchao DAI
- Publication Type:Journal Article
- Keywords:
anesthesia;
ventricular septal defects;
child;
interventional therapy;
ketamine;
propofol;
sevoflurane
- From:
Chongqing Medicine
2013;(25):2986-2987,2990
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the proper anesthetic administration schemes in pediatric patients undergoing surgery of transcatheter ventricular septal defect closure .Methods A total of 120 pediatric patients with congenital heart diseases of ventricu-lar septal defect ,aged 3-9 years old with ASA physiological status Ⅰ or Ⅱ ,undergoing surgery of transcatheter ventricular septal defect closure were randomly divided into 4 groups with 30 each :ketamine group( K group) ,propofol group( P group) ,ketamine associate with propofol ( KP group) ,sevoflurane group( S group) .Spontaneous respiration were maintained in K ,P ,PK groups ,but mechanical ventilation was adopted after endotracheal tube intubation in S group .The values of MAP ,HR ,SpO2 ,RR were recorded at the following time points :before anesthesia ,incision immediate ,procedure in heart ,completion of operation ,and 30min after oper-ation .awaking time and adverse reactions were recorded .Results Anesthesia and operation were carried out successfully in all pa-tients .Awaking time in P group and KP group markedly shorter than K group (P<0 .01) .The incidence rate of adverse reactions such as cough ,asphyxia and body motion in pediatric patients by mechanical ventilation and sevoflurane inhaled markedly less than other groups(P<0 .01) .Conclusion It is safe that pediatric patients received mechanical ventilation and sevoflurane inhaled after endotracheal intubation undergoing surgery of transcatheter ventricular septal defect closure .