A Case of Large Cell Neuroendocrine Carcinoma accompanied with Adenocarcinoma of the Uterine Cervix.
- Author:
Yu Re KIM
1
;
Man Gi KIM
;
Kyu Sang KYEONG
;
A Ra JO
;
Seung Hwa HONG
;
Yeon Jin PARK
;
Ill Woon JI
;
Eun Hwan JEONG
;
Hak Soon KIM
;
Ok Jun LEE
Author Information
1. Department of Obstetrics and Gynecology, Chungbuk National University College of Medicine, Cheongju, Korea. hakskim@cbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Large cell neuroendocrine carcinoma;
Cervical cancer
- MeSH:
Adenocarcinoma*;
Carcinoma, Neuroendocrine*;
Cervix Uteri*;
Combined Modality Therapy;
Diagnosis;
Female;
Humans;
Keratins;
Middle Aged;
Neoplasm Metastasis;
Phosphopyruvate Hydratase;
Prognosis;
Recurrence;
Synaptophysin;
Uterine Cervical Neoplasms;
Vimentin
- From:Korean Journal of Obstetrics and Gynecology
2006;49(9):2004-2011
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Large cell neuroendocrine carcinoma of the uterine cervix is a rare and highly aggressive cervical neoplasm. Metastases and recurrences of the tumor are common. Cervical large cell neuroendocrine carcinomas are distinctive cervical carcinomas that are frequently misdiagnosed and have unfavorable prognosis. So prudential care must be considered for proper diagnosis and multimodal treatment may be required for better survival. We experienced one case of large cell neuroendocrine carcinoma accompanied with adenocarcinoma of the uterine cervix in 52 year old woman. The uterine cervix covered and infiltrated with adenocarcinoma cells and attached polypoid mass (3.2 x 2.1 cm) composed of large cell neuroendocrine carcinoma cells. The diagnosis was confirmed by immuno-staining using cytokeratin (+), synaptophysin (+), chromogranin (+), neuron-specific enolase (+), CD 56 (+), and vimentin (-). So we report the case with brief review of the literature.
