A randomized double-blind control study on oxiracetam and donepezil in treating Alzheimer disease
- VernacularTitle:奥拉西坦与盐酸多奈哌齐治疗阿尔茨海默病的随机双盲对照研究
- Author:
Jianliang NI
- Publication Type:Journal Article
- Keywords:
oxiracetam;
donepezil;
Alzheimer disease
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To compare the efficacy and safety of oxiracetam and donepezil in treating Alzheimer disease with mild and moderate MMSE scores.METHODS: 68 patients were randomly divided into oxiracetam group(p.o.,n=34) and donepezil group(p.o.,n=34).The MMSE and Blessed-Roth measuring scales were used to evaluate the curative effects before treatment and three months after treatment.RESULTS: There were significant differences between the indexes expect for activities of daily living before and after treatment in two groups(P0.05).CONCLUSION: The curative effect and safety of oxiracetam and donepezil in treating mild and moderate Alzheimer disease are similar.
