Progress of CD4~+CD25~+ regulatory T cells in rheumatoid arthritis
- VernacularTitle:CD4~+CD25~+调节性T细胞在类风湿性关节炎中的研究进展
- Author:
Tingyu WANG
;
Jun LI
- Publication Type:Journal Article
- Keywords:
rheumatoid arthritis;
CD25;
suppressor;
regulatory T cells
- From:
Chinese Pharmacological Bulletin
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
CD4+CD25+ regulatory T cells(CD4+CD25+Tregs),a suppressor T cell population,have been shown to play an important role in maintaining peripheral tolerance and the prevention of autoimmunity.This review summarizes the characteristics and mechanism,as well as their role in rheumatoid arthritis(RA).An understanding of these issues is likely to facilitate the development of CD4+CD25+Tregs-cell-based therapies for the treatment of RA.
