Determination of berberine hydrochloride in Fuyanping capsules by HPLC
- VernacularTitle:高效液相色谱法测定妇炎平胶囊中盐酸小檗碱含量
- Author:
Ying ZHAI
;
Xu CHEN
;
Weiyi LIU
;
Yikun SUN
- Publication Type:Journal Article
- Keywords:
Berberine hydrochloride;
Fuyanping capsules;
HPLC
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality standard of berberine hydrochloride in Fuyanping capsules by HPLC. Methods:HPLC with Phenomenex C18(250?4.6mm,5?m)column was used.Acetonitrile-0.033mol/l potassium dihydrogen phosphate(30:70)was used as a mobile phase,flow rate was 1.0ml/min and detection wavelength was set at 346nm.Results: Berberine hydrochloride showed a good linear relationship at a range of 0.16-0.83?g,r=0.9999.The average recovery was 99.09%,and RSD was 0.20%.Conclusion:This method is simple,fast and accurate for the quality control of Fuyanping capsules.
