Plasma level of endogenous hydrogen sulfide in patients with acute asthma
- VernacularTitle:支气管哮喘患者血浆中硫化氢的变化及其意义
- Author:
Rui WU
;
Wanzhen YAO
;
Yahong CHEN
;
Bin GENG
;
Chaoshu TANG
- Publication Type:Journal Article
- Keywords:
Asthma;
Hydrogen sulfide;
Lung diseases
- From:
Journal of Peking University(Health Sciences)
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the role of endogenous hydrogen sulfide(H2S)in patients with asthma.Methods:Levels of serum H2S,lung function and cell differential count in induced sputum were studied in 44 patients with acute exacerbation of asthma,33 patients with stable asthma and 12 health subjects.Of the 33 patients with stable asthma,3 failed to achieve induced sputum.Results:The serum H2S level was(75.2?13.0)?mol/L in controls(12 cases),(55.8?13.6)?mol/L in patients with stable asthma(33 cases),(57.8?6.3)?mol/L in patients with mild of acute exacerbation asthma(9 cases),(40.8?5.1)?mol/L in that with moderate of acute exacerbation asthma(13 cases),and(31.3?2.9)?mol/L in that with severe of acute exacerbation asthma(22 cases,F=44.592,P
