The Relationship between the Blood Pressure in Subjects with Impaired Glucose Relation and the Tirst-phase Insulin Secretion
- VernacularTitle:IGR患者的血压水平与胰岛素早期分泌功能的关系研究
- Author:
Qiuling ZHANG
;
Lan SHOU
;
Xuefeng HUANG
;
Rongfang TANG
- Publication Type:Journal Article
- Keywords:
Impaired glucose relation;
Hypertension;
Insulin resistance
- From:
Journal of Medical Research
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the blood pressure in subjects with impaired glucose relation and the first-phase insulin secretion.Methods The oral glucose tolerance test was performed in 126 subjects who were divided into normal blood pressure group higher blood pressure group and hypertension group.The beta-cell function was calculated by HOMA-IR and △I30/△G30.Results ①The BMI and WHR were significantly higher in hypertension group.The serum level of lipids was changed in higher blood pressure and hypertension groups.② The fasting plasma insulin level,60、120 minutes insulin level after oral 75 game glucose were significantly higher in hypertension group.③ The HOMA-IR was significantly higher in higher blood pressure and hypertension groups,with more higher in hypertension group.④ The △I30/△G30 was significantly decrease in hypertension group.There are no different in other groups.Conclusion The higher blood pressure,the more severe insulin resistance,the more decrease first-phase insulin secretion.
