Progress in mechanism of specific immunotherapy
10.3760/cma.j.issn.1673-4408.2011.03.011
- VernacularTitle:特异性免疫治疗机制的研究进展
- Author:
Yaqiong HU
- Publication Type:Journal Article
- Keywords:
Specific immunotherapy;
Mechanism
- From:
International Journal of Pediatrics
2011;38(3):238-241,244
- CountryChina
- Language:Chinese
-
Abstract:
Specific immunotherapy(SIT)is the most effective therapy for allergies.Although specific immunotherapy has existed for more than 90 years and has made a great progress,its mechanism is not well defined.Early studies focused on the circulating antibodies and effector cells.At present.the research of the mechanism mainly concentrates on the immune therapy on T cells role and a series of cytokines arising from the change,CD4+ regulatory T cells subsets,modified APC induction of immune tolerance,aggregation mechanism of immune effector cells,restructuring allergens under the support of monoclonal antibody technique,allergens DNA vaccines,allergens coupling adjuvants.This essay is a review of progress in mechanism of specific immunotherapy.
