Research on Correlation between Selenium Level and Cognitive Function for Rural Elderly Population in China
- VernacularTitle:重组人生长激素治疗前后血胰岛素样生长因子-Ⅰ、胰岛素样生长因子结合蛋白水平监测及意义
- Author:
Zhaohui CUI
;
Jidong WANG
- Publication Type:Journal Article
- Keywords:
rhGH;
IGF-Ⅰ;
IGFBP3;
Tumor
- From:
Journal of Medical Research
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safeness of this treatment by comparing the serum IGF-Ⅰ and IGFBP3 concentration level before and after receiving rhGH treatment in pediatric patients.Methods 30 pediatric patients in our hospital receiving rhGH treatment were subjected to monitor serum IGF-Ⅰ and IGFBP3 level before and after the treatment and calculate the IGF-Ⅰ and IGFBP3 ratio.At the same time the serum T3,T4 and TSH are also assayed.Results The average increase of booly heights was(8.77?3.01)cm /y(t=7.773,P0.05),but the serum IGFBP3(t=3.759,P0.05).However,there was statistical significance of the serum IGFBP3 level between subgroups(f=22.964 P0.05).Conclusion The serum IGF-Ⅰ and IGFBP3 level are able to be used as one of clinical evaluation benchmarks to detect the risks of inducing tumor during the rhGH treatment in the pediatric patients.