Effect of Atorvastatin on Cardiac Function and Plasma C-reactiveprotein and Uric Acid Elevels in Patients Ischemic Cardiomyopathy
- VernacularTitle:阿托伐他汀对缺血性心肌病患者心功能及血清C-反应蛋白、尿酸水平的影响
- Author:
Mingchun LI
;
Jilie LIU
- Publication Type:Journal Article
- Keywords:
Atorvastatin;
Ischemic cardiomyopathy;
C-reactiveprotein;
Uric acid
- From:
Journal of Medical Research
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of atorvastatin on ischemic cardiomyopathy patients with chronic heart failure and to investigate the changes of serum levels of CRP and serum levels of uric acid after treatment.Methods Fifty patients with ischemic cardiomyopathy(NYHAgradeⅡ～Ⅳ) were randomly divided into two groups: the therapy group received atorvastatin 10mg/d(n=25) for 4 weeks and the control group received placebo(n=25).In addition,20 healthy peoples were observed.Before and after treatment,the parameters of plasma uric acid,serum CRP and cardiac function evaluated by echocardiogram were measured.Results After 4 weeks,patients receiving atorvastatin exhibited a modest reduction in serum CRP and serum uric acid compared with control group(P
