Effects of Chaiyuwendan Decoction on ethology and monoamine neurotransmitters in brain of depressive disorder rats
- VernacularTitle:柴郁温胆汤对大鼠抑郁模型行为学及脑内单胺类神经递质的影响
- Author:
Haihong ZHOU
;
Fan LU
;
Yanling CHEN
;
Hongmei ZHU
;
Xun WANG
;
Jiyuan HU
;
Yongzhu HAN
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Chaiyuwendan Decoction;
Ethology;
Monoamine neurotransmitter;
Rat
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the anti-depression mechanism of Chaiyuwendan Decoction(CYWDD).Methods:Rat models were established by separation and chronic unpredictable mild stress(CUMS).Ethology of rats were detected by open-field test and sucrose consumption test,contents of monoamine neurotransmitters were detected by HPLC-ECD.Results:Compared with normal group,the weight,the frequency of crossing,rearing and the contents of consumption to sucrosum water in depressive disorder rats decreased significantly(P
