Clinical analysis on 5 cases of critically ill children complicated with pancreatic necrosis
10.3760/cma.j.issn.1673-4912.2011.02.007
- VernacularTitle:危重患儿胰腺坏死五例临床分析
- Author:
Yimin ZHU
;
Fang LIU
;
Weijian CHEN
- Publication Type:Journal Article
- Keywords:
Pancreatic necrosis;
Critically illness;
Multiple organ failure;
Children
- From:
Chinese Pediatric Emergency Medicine
2011;18(2):120-122,后插一
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical features and biological markers of critically ill children with pancreatic necrosis. Methods The clinical data of 5 ill children whose autopsy confirmed pancreatic necrosis in our hospital from 2003 to 2009 were collected and the pathological results were analyzed.Results Five cases appeared as acute onset and fever. Clinical manifestation of 2 cases included abdominal pain and 2 cases represented abdominal bulging,lots of flatulence and gastrointestinal bleeding. Four cases represented abnormal liver function and significant decrease of albumin,3 cases with increase of C-reactive protein. No case showed abnormal pancreas acoustic image of abdominal B-ultrasonography. Autopsy confirmed that 5 cases represented varying degrees necrosis of the pancreas, which complicated with the damage of adrenal gland,liver,lung,heart, spleen, kidney,intestine, thymus, mediastinal and mesenteric lymphnodes. All died in 36 hours after the children'conditions were changed. Two cases died of acute hemorrhagic necrosis of the pancreas,3 cases died of multiple organ failure based on pancreatic necrosis. Conclusion Pancreatic necrosis in critically ill children presents acute onset and short course,is prone to result in multiple organ damage or failure.
