Correlation between the excretive level of urinary albumin and the diabetic retinopathy in members of type 2 diabetes mellitus pedigree
- VernacularTitle:2型糖尿病家系成员尿白蛋白排泄率与糖尿病视网膜病变的关系
- Author:
Wei SHAO
;
Wei REN
;
Suhua ZHANG
- Publication Type:Journal Article
- Keywords:
diabetes mellitus,type 2;
albumin uria;
diabetic retinopathy
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the excretive level of urinary albumin(ELUA) and the diabetic retinopathy(DR) in type 2 diabetes mellitus(DM) pedigree.Methods Sixty-five type 2 diabetes mellitus families including 476 persons were enrolled in the present study.All of them were divided into normal glucose tolerance group(NGT,140 persons),impaired glucose regulation group(IGR,93 persons),diabetes mellitus group(DM,164 cases) and diabetic retinopathy group(DR,79 cases).The cases in DR group were further divided into background group(BDR,66 cases) and proliferation group(PDR,13 cases) according to the findings of oral glucose tolerance test(OGTT),fundus fluorescence angiography and fundus examination.The levels of blood pressure(BP),fasting blood glucose(FBG),postprandial blood sugar(PPBS),lipid,serum creatinine(Cr),blood urea nitrogen(BUN) and ELUA were determined.The correlation analysis and multiple regression analysis were performed between the ELUA and other parameters.Results There was an increasing trend of ELUA in the NGT,IGR,DM and DR groups,and there existed significant differences in ELUA among the four groups(P0.05).A positive correlation was found by Spearman rank correlation analysis between ELUA and diastolic blood pressure(DBP) in DR group(P
